The Epilepsy Center (EC) is considered as reference for referring epilepsy patients from around the country, particularly those that are difficult to diagnose or present forms of refractory epilepsy. EC makes efforts to the promotion and prevention of epilepsy, and intervention for most patients with epilepsy regain health. Not confined to hospital care, but strategies are designed to reach the community. The proposed actions produce results in the short term.

Epilepsy and Pharmacology

The 61% of patients have adverse drug reactions (ADR) with antiepileptic drugs (AED), in 40% determining discontinuation due to toxicity.
The goal in treating epilepsy is control seizures, but also prevents adverse events (AE). International League Against Epilepsy (ILAE) has recognized AE assessing outcome in epilepsy treatment.
Among the most frequent ADR are cognitive changes and their impact on quality of life. Few studies have assessed them using neuropsychological test.
Other frequent AE are severe adverse skin reactions, especially DRESS.
Clinical judgment is sufficient to evaluate AE. However, there are AE that rely on patient's subjective complaints and systematic questionnaire. There is underreporting of AE. A checklist allows systematic monitoring of AE produced by AED.
We evaluate cognitive changes and their impact on quality of life, the occurrence of rash and a checklist to increase reports of AE to reduce morbidity, promoting rational use of AED.

Investigation of Genetics Factors Contributing to Diagnosis and Treatment of Epilepsy

Epilepsy is one of the most prevalent neurological disorders, affecting about 3% of world population. Even though, the vast majority of patients respond well to different anti-epileptic drugs, there remain a 30% of subjects non-responsive to medical treatment. It is still not completely understood the reason and mechanisms involved in the so-called phenomenon of drug-resistance in epilepsy. Genetic factors could be involved in these processes. Epilepsy secondary to Malformations of Cortical Development is one the frequently drug-resistant syndromes in infancy. We propose to advance in the knowledge of the genetic factor responsible for some of the malformations of cortical development applying classic strategies of molecular genetics as the most news tools such as next generation sequencing in a clinical epileptology setting.

Maternity and Epilepsy

More information coming soon...

Epilepsy and Sleep

Biological rhythms are inherent to all living systems. These rhythms are originated within each organism and modulated by environmental stimuli. It has been reported that alteration in these circuits, for example the decrease in the inhibitory GABAergic system, causes a reduction in the CNS epileptogenic threshold. Despite the controversies in the literature on the relationship between epilepsy and sleep, there is evidence to assume that sleep act is a natural protector of epilepsy. With the hypothesis that central biological rhythms are altered in this population, we studied the clinical, EEG, and subjective quality and architecture of nocturnal sleep in patients with seizures only during sleep.

Magnetic Resonance Images & Diffusion Tensor Images in Epilepsy

More information coming soon...

Malformations of Cortical Development and Epilepsy

Malformations of cortical development (MCD) are responsible for a wide spectrum of clinical manifestations that include epilepsy, mental retardation and neurological deficits. MCD are considered the second most common cause of medically refractory partial epilepsy in adults after hippocampal sclerosis. Diagnosis of MCD has notably been improved in the past 2 decades as a result of advances in modern imaging, especially magnetic resonance imaging (MRI), and genetics. Epilepsies that were considered cryptogenic in the past are now recognized as secondary to MCD.
A detailed assessment of MRI features allows determining the MCD subtype according to Barkovich classification scheme, which can be summarized by 3 main groups:
Group 1: “malformations due to abnormal cell proliferation”
Group 2: “malformations due to abnormal migration”
Group 3: “malformations due to abnormal cortical organization”
Several variables are included in the studies that are conducted in our centre: demographic data and clinical features of epilepsy, EEG findings (both the EEG interictal and ictal EEG video registers) and type of response to treatment.

Among epilepsy secondary to alterations of neuronal proliferation, are the focal cortical dysplasia identified by MRI. These patients often lack pharmacological control, considering the surgical alternative. One of the most valuable resources for defining the neural network involved in the epileptogenic zone (EZ) is the high definition electroencephalogram (EEG). Applying mathematical algorithms , solving the “inverse problem”, we try to locate the sources of epileptic discharge. From the field of the dipole we localized interictal spike that best explains the pattern of surface EEG. These source localization techniques are less aggressive and expensive, if proven its usefulness, to facilitate location of EZ and contribute to the understanding of cortical neuronal connectivity.

Consciousness and Epilepsy

Consciousness is a multifaceted concept is defined as the ability of the person to maintain alertness, attention and knowledge of self and environment. Based on various studies show that it depends on the normal activity of a cortical neural network, particularly large cortical association areas located at the fronto-parietal, and its modulation by subcortical system located at the brain stem and diencephalon.
Epileptic seizures are expressed by sudden changes in the behavior of short duration, 1 to 3 minutes, most of the time show disturbance of consciousness, and this is one of the aspects that affect the quality of life of the patients.
Despite the different investigations both experimentally and clinically, there is no clear explanation of why this impaired of consciousness happens. The understanding of the underlying mechanisms of consciousness would modify treatments to avoid such disturbance during a crisis. To this end we evaluated demographic variables, characteristics of altered consciousness, the surface and intracerebral EEG records and brain MRI.

Studies of electrical and clinical semiology of epileptic seizures

More information coming soon...

The Advanced Center of Intracerebral Recordings (ACIR) is the first center in Latin American to have the necessary equipment for human single cell recording in order to study more precisely the origin of epileptic seizures. The ACIR was inaugurated on August 3rd 2012 and is part of the Epilepsy Center who has dual membership: Neurology Division, Ramos Mejía Hospital and Epilepsy Laboratory, Institute of Cellular Biology and Neuroscience "Prof. Dr. E. De Robertis" (University of Buenos Aires - National Council for Scientific and Technical Research).

Single Cell Recording

The Advanced Center of Intracerebral Recordings count with necessary equipment and human resources capable of register the activation of single neuron. The acquisition of this new technology puts Argentine as one of the few countries in the world (USA, England, France, Germany, Holand), and first in Latin America capable of performing such a study.
The Advanced Center of Intracerebral Recordings is part of the Epilepsy Center (EC) of Ramos Mejía Hospital. The EC is a high complexity center for outpatients care, being considered as reference for referring patients from around the country and neighboring countries. The EC counts with a video unit-EEG, where patients are admitted for continuous recording during 7-10 days.

Studied population

Patients who do not become seizure-free with the current pharmacological treatments go to EC to perform video-EEG studies, neuropsychological and psychiatric assessment, MRI and fMRI studies, among others. With this studies, the EC specialist can design surgical strategy according each patient.
Most of the time, the surgery of epilepsy, which removes the portion of the brain where seizures originate (epileptogenic zone), is the next step of these patients to become seizure-free.
In some cases, the information obtain with non-invasive methods is not enough to delimit the epileptogenic zone, for which is explored by intracerebral electrodes in specific areas of the brain which vary from each patient.
Thus, for clinical reasons there is the unique opportunity to make a direct recording of brain activity in humans, both large group of neurons and single neurons in patients candidates for epilepsy surgery.

Equipment

Motivated by technological advances, the Advanced Center of Intracerebral Recordings has acquired the elite system of Blackrock Neuromed (Utah, USA) for simultaneous recording of 128 channels of microelectrodes and macroelectrodes. Microelectrodes are used for single cell recordings, while macroelectrodes are used for intracerebral EEG (iEEG) recordings. This system, which combines in one device the two type of recordings, improves the conditions used so far in the best centers of the world.
The traditional iEEG capture the electrical activity of millions of neurons simultaneously. This new technique used microelectrodes of 40 micrometers thick placed in specific brain areas, which are believed from several clinical studies, could be the epileptogenic zone. Each of these microelectrodes records the activity of a small group of neurons (2-3) and with the use of mathematical algorithms can differentiate the electrical activity of neurons one by one. It is important to note that the placement of the microelectrodes do not imply additional risk, since they are located inside the electrodes normally used for iEEG, protruding 3-4 mm from the end of macroelectrode.

Objectives and Implications

The advantage essentially consists in register and differentiate the electrical activity of a single neuron from other, instead of recording the activity of millions of neurons as occurs until now with surface electrodes and intracerebral macroelectrodes.
This will not only allow greater accuracy when defining the epileptogenic zone, but also explore new treatments. The higher risk of epilepsy is that it cannot predict.
The increased risk of epilepsy is that you cannot predict the onset of the crisis, with an uncertainty factor for patients. Although clinically crises seem to come without warning, there is much evidence that the neural network begins to prepare before what the subject perceives. Therefore, the possibility of such registrations will obtain, applying prediction algorithms, better information on how to prepare the epileptogenic network and possibly in the future, develop treatments that prevent the onset of the seizure. At the same time, this procedure allows research the neurophysiological bases of different cognitive processes, chiefly perception and memory, as well as motor activity. In the patients with epilepsy exist a brain region that functions badly in a specific moment, but then is normalized enabling the comprehension of brain operation. By this, the epilepsy is a model that allows study the cognitive capabilities.

Main Collaborator

Rodrigo Quian Quiroga. Director of the Centre for Systems Neuroscience & Head of the Bioengineering Research Group, University of Leicester, United Kingdom.

Localization and characterization of brain activity sources

The overall goal is to develop methods and algorithms to model, locate and characterize the neuronal populations sources of interest in the study human brain functions from electroencephalography (EEG), intracranial EEG and magnetic resonance imaging (MRI). Applications focus locating sources in epilepsy, as well as in the study of normal brain, through the use of event related potentials. The results are contrasted with those obtained by other techniques such as functional MRI (fMRI), diffusion tensor imaging (DTI), clinical correlation of the crisis (video-EEG) and, where feasible, with data from electrical stimulation and cortical resection surgery.

Different source localization techniques are used to solve the inverse problem. Realistic models of electrical conductivity are made using finite element method (FEM) and boundary element method (BEM). The distributed or dipolar source models are used depending on the particular application.

In order to obtain a greater degree of realism, "Physiologically plausible neural populations models" are used. This gives a different perspective to the modeling of brain activity sources, considering both the nonlinear dynamics of neuronal behavior, as well as the complex network of connections between neuronal populations. These models allow a detailed description of epileptogenic sources, among other parameters controlling connectivity among epileptogenic and non epileptogenic populations.

Main Collaborator

Carlos Muravchik
Director of Signal Processing, LEICI, Faculty of Engineering, National University of La Plata.

Professional team

The Advanced Center of Intracerebral Recordings is formed by an interdisciplinary working group, that includes the following disciplines: neurology, neurosurgery, neuropsychology, biomedical engineering, biology, psychiatry, and medical images.

External Collaborators

This new system, that allow register a single neuron electrical activity was developed in the '70s in the University of California, LA (USA). The arrival to Argentina of this technology was possible thanks to the contribution of the Argentine Physicist Rodrigo Quian Quiroga, head of Biophysicist Department and professor of Bioengineering in the University of Leicester, United Kingdom, who is working with this technique ten years ago.
The collaboration with Dr. Quian Quiroga starts in the `90s and in the last year a joint work was initiated to install in Argentina the same setup that is installed in Leicester to single cell recordings during visual perception tasks.
Dr. Quian Quiroga possesses a vast experience and has developed the algorithm of spike sorting, which allows to recognize the electrical activity of a neuron particularly differentiating it of the others. During August of 2012, we have counted with the presence of Dr. Quian Quiroga in the EC to attend the inauguration of the Advanced Center of Intracerebral Recordings, and to supervise the setup for the registration with microelectrodes.
We have also counted with the contribution of Dr. Bekinschtein, of the MRC-Cognition and Brain Sciences Unit, University of Cambridge, UK, in the study of Local Field Potentials (LFP) and Event-Related Potentials (ERP).
At the same time, it will continued with the contribution of Dr. Muravchik, director of the LEICI laboratory, Faculty of Engineering, National University of La Plata, to continue with the study of characterization and locating of sources in epilepsy. Dr. D'Attellis, director of the Department of Mathematics at Favaloro Foundation and director of the Department of Mathematics at National University of San Martín will lead the seizure prediction studies with the obtained data.

The Clinic and Laboratory of Neurogenetics at the Neurology Service in the JM Ramos Mejia Hospital specializes in the care of patients and families affected by central nervous system diseases that have or may have a hereditary basis in its development.

Since its inception in 2008, we have carried out simultaneously care, teaching and research in the field of Clinical Neurogenetics.

The office works with general neurologists or sub-specialized in different areas of Neurology, offering advice on the diagnosis and genetic counseling of patients and families affected by diseases caused by genetic alterations.

Among the various pathologies that are often assisted in the office, familial epilepsies stand out. Furthermore, we can mention spinocerebellar ataxia, Friedreich's ataxia, dystonia, Huntington's disease, and mitochondrial neurometabolic disorders, leukodystrophies and hereditary Polyneuropathies (Charcot -Marie-Tooth).

The office works in the Department of Neurology of the Ramos Mejia Hospital in Buenos Aires, Argentina and is led by Dr. Marcelo Kauffman, Medical Neurologist, Master of Medical Molecular Biology. Dr. Dolores González Morón, Dr. Sergio Rodriguez, Quiroga, Dr. Patricia Vega and Dr. Marta Córdoba participate in patient care and research and teaching duties, too.

Lines of Research

Study of the genetic mechanisms underlying the malformations of cortical development.

Hypothesis and general objective

Many Malformations of Cortical Development (MDC) are caused by genetic defects. Although several genes involved in the pathogenesis of these disorders have been recognized, it is still large the number of subjects with no individualization of MDC genetic etiopathogenesis. Therefore, our hypothesis is that mutations in different functional genes in the development of central nervous system represent a frequent cause of Malformations of Cortical Development and the overall goal of the project is, then, contribute to the knowledge of the mechanisms involved in the genesis of Malformations of Cortical Development, particularly the identification of mutations making aetiopathogenic in a population of patients with them.

Research Objectives

1. Determine in a population of patients with epilepsy secondary to periventricular nodular heterotopias from Argentina the prevalence of mutations in filamin A (FLNA).

2. Discover new pathogenic mutations in FLNA, ARFGEF2, YWHAE and PQBP1 genes in the study of the etiology of epilepsy secondary to periventricular nodular heterotopias.

3. Discover new pathogenic mutations in the doublecortin gene in the study of the etiology of epilepsy secondary to subcortical band heterotopias.

4. Determine in a population of patients with epilepsy secondary to Polimicrogirias from Argentina the prevalence of mutations in the genes encoding Tubulins.

Genomic Diagnosis in the study of neurogenetic diseases

Hypothesis and objective:

Many of the Nervous System Diseases are caused by genetic defects. Although several genes involved in its pathogenesis have been recognized, it is still large the numbers of subjects with neurological disorders without identification of their genetic etiology. On the other hand, new massive genome sequencing technologies are called to produce a paradigm shift in the approach to diagnosis of disease, predicting a noticeable short-term impact on the study of the molecular causes of monogenic disorders. Therefore, our hypothesis is that mutations in different functional genes in the development and function of the nervous system represent a significant etiology of Neurological Disorders and developing a systematic genomic analysis oriented will impact clinical diagnostic practice of Hereditary disorders of the nervous system and the overall goal of the project is, then, contribute to the study of neurogenetic diseases through massive genomic sequencing in a population of patients.

Specific objectives:

Our specific objective of work is the recognition of new genes involved in the pathogenesis of monogenic neurogenetic disorders familiarly aggregated by using massive genome sequencing platforms. We propose in particular:

1. Explore the use of different bioinformatics tools in analyzing data obtained through massive genomic sequencing through the implementation of an algorithm for annotation and classification of genetic variants identified.

2. Generating a meta-tool that combines bioinformatics existing analytical resources correlating usual medical narrative (history), genotypes and biomedical literature.

The main objectives of neuropsychological assessment of patients with epilepsy are:
1. To determine the patient’s baseline cognitive status.
2. To establish hemispheric dominance for language.
3. To identify focal functional deficits associated with the location and laterality of the epileptogenic zone.
4. To determine the probability of postsurgical cognitive changes.
Our group develops clinical and research work mainly focused to the population of patients with drug-resistant epilepsy that are candidates for surgery.

Current research

- Study of the persistence of long-term memory before and after surgery through different memory tasks: face memory, musical memory and emotional memory.
- Features and persistence of autobiographical memory in patients with drug-resistant epilepsy before and after surgery.
- Functions of dominant and non-dominant hemisphere: Determination of logical and social aspects of language and communication, and its relation with people’s communication skills.
- Social cognition: Study of emotion recognition through facial, body and prosodic/ musical expression, theory of mind and social interaction skills.
- Study of the cognitive effects of antiepileptic drugs.

Neurobiological and behavioral aspects in people with epilepsy

a- Neurobiological aspects of epilepsy, determination of biochemical markers related to brain neuroplasticity in patients with surgical treatment; histological and neurochemical study of tissue removed during surgery.

b- Behavioral aspects. Research on the behavioral characteristics that affect the quality of life of patients, determining the presence of disorders plausible treated of interdisciplinary team of Mental Health; comorbidity with mood disorders, anxiety, substance abuse and psychosis and personality disorders. Evaluation of patients with epilepsy surgery.

c- Analysis of the prevalence of CNE-P (non-epileptic seizures of psychogenic origin); paroxysmal changes in behavior, sensory perception and / or cognitive activity, simulating generalized or partial seizures, but they are not due to a neuronal discharge, and they are associated with psychiatric disorders. PNES are confused with the epilepsy and are often underdiagnosed. The CNEP require an interdisciplinary approach by Mental Health team.

Inhibition of epileptic discharge by high and low frequency stimulation in an experimental model of epilepsy

Epileptic seizures involve sudden changes in neuronal activity which interfere with the normal operation of the neural network, expressing through hypersynchronous discharges of neuronal populations affected. In the last decade it has been proposed to deep brain stimulation (DBS) as an alternative treatment for patients who do not become seizure-free with the current pharmacological treatments and cannot undergo resective surgical procedure of the epileptogenic zone. However, it remains to determine the optimum stimulation parameters.
In our laboratory, the animals are implanted by stereotaxic surgery with stimulation and recording electrodes. The process of epileptogenesis is studied by applying the kindling model, which consists of a single periodic stimulation in a specific brain area for approximately 30 days, giving rise to the appearance of focal seizures secondarily generalized. Currently, our laboratory applies a variable of this phenomenon called Rapid Kindling (RK). Unlike the kindling, in RK is repeated electrical stimulation several times a day for three consecutive days, accelerating the epileptogenic process. To study the effect of the high (HFS) or low frequency (LFS) electrical activity as a potential inhibitor of seizures, it applies HFS or LFS immediately prior to kindling stimulation. It register the electrical activity of the animal pre- and post-stimulation and its analyzed the behavioral response of the animal, as well as different parameters of the electroencephalogram (EEG). This information allows for the antiepileptogenic effect which could cause the stimulation of high and low frequency, delaying the development of the Kindling phenomenon and reducing the post-discharge.
High (HFS) and low (LFS) frequency stimuli act by inhibiting the neural network organization involved in epileptogenesis, thus preventing hypersynchronous discharges.

2012

“Postoperative Neuropsychological Outcome in Patients with Mesial Temporal Lobe Epilepsy in Argentina”
Oddo S, Solis P, Consalvo D, Seoane E, Giagante B, D'Alessio L, Kochen S. Epilepsy Research and Treatment (2012); Article ID 370351, 5 pages. doi: 10.1155/2012/370351.
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"Non-invasive approach to Focal Cortical Dysplasias: clinical, EEG and neuroimaging features."
Seifer G, Blenkmann A, Princich JP, Consalvo D, Papayannis C, Muravchik C, Kochen S. Epilepsy Research and Treatment (2012), Article ID 736784, 10 pages. doi: 10.1155/2012/736784.
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“Malformations of cortical development and epilepsy in adult patients”
Papayannis CE, Consalvo D, Kauffman MA, Seifer G, Oddo S, D'Alessio L, Saidon P, Kochen S. Seizure: European Journal of Epilepsy (2012); 21(5): 377–84. doi: 10.1016/j.seizure.2012.03.009.
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“Contribution of diffusion tensor magnetic resonance imaging to the diagnosis of focal cortical dysplasias”
Princich JP, Consalvo D, Kauffman M, Seifer G, Blenkmann A, Kochen S. Revista de Neurología (2012); 54(8):453-60.
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"Cerebrotendinous Xanthomatosis revealed in Drug-Resistant Epilepsy Diagnostic Work-Up"
Kauffman MA, Gonzalez-Morón D, Consalvo D, Kochen S. Am J Med Sci (2012); 343(4):332-3.
doi: 10.1097/MAJ.0b013e31823cf6d8.
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“Effect of unilateral low-frequency stimulation of hippocampus on rapid kindling - induced seizure development in rats”.
Toibaro L, Pereyra M, Pastorino J, Ortmann G, Galardi M, Gori MB, Kochen S. Neuroscience & Medicine (2012); 3:174-80. doi:10.4236/nm.2012.32022
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“Motor-language coupling: Direct evidence from early Parkinson's disease and intracranial cortical recordings”.
Ibáñez A, Cardona JF, Dos Santos YV, Blenkmann A, Aravena P, Roca M, Hurtado E, Nerguizian M,Amoruso L, Gómez-Arévalo G, Chade A, Dubrovsky A, Gershanik O, Kochen S, Glenberg A, Manes F,Bekinschtein T. Cortex (2012); Mar 8. [Epub ahead of print]
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“Diagnosis of mitochondrial disorders applying massive pyrosequencing.”
Kauffman MA, Gonzlez-Morón D, Consalvo D, Westergaard G, Vazquez M, Mancini E, Taratuto AL, Rey R, Kochen S.
Mol Biol Rep (2012); 39(6):6655-60. doi: 10.1007/s11033-012-1471-9.
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“Alteraciones extrahipocámpicas en epilepsia temporal mesial con esclerosis del hipocampo”
Consalvo D, Kauffman M, Oddo S, Rey R, Kochen S. Neurología Argentina (2012); 4(2):53–58.
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“Crossed aphasia after right anterior temporal lobectomy. A case report”
Múnera CP, Lomlomdjian C, Solis P, Medel N, Kochen S. Epilepsy & Behavior (2012); 25(1):125-8.
doi: 10.1016/j.yebeh.2012.05.014.
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“Psicosis y epilepsia: características clínicas y abordaje terapéutico”
D'alessio L, Donnoli V, Kochen S. Vertex Revista Argentina de Psiquiatría (ISSN 0327-6139) (2012); 23(104).
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"SLC6A4 gene variants and temporal lobe epilepsy susceptibility: a meta-analysis”.
Córdoba M, Consalvo D, Moron DG, Kochen S, Kauffman MA. Mol Biol Rep (2012); 39(12): 10615-9.
doi: 10.1007/s11033-012-1949-5.
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“Association between equivalent current dipole source localization and focal cortical dysplasia in epilepsy patients.”
Blenkman A, Seifer G, Princich JP, Consalvo D, Kochen S, Muravchikc C. Epilepsy Res (2012); 98(2-3):223-31.
doi: 10.1016/j.eplepsyres.2011.09.018.
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2011

“Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic antipiletic drugs”
Pereira da Silva N, Piquioni P, Kochen S, Saidon P. Eur J Clin Pharmacol (2011);67(5):463-70.
doi: 10.1007/s00228-011-1005-8.
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“Psychosis after epilepsy surgery: Report of three cases.”
Calvet E, Caravotta PG, Scévola L, Teitelbaum J, Seoane E, Kochen S, D Alessio L. Epilepsy Behav (2011); 22(4):804-7. doi: 10.1016/j.yebeh.2011.09.029.
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“Pregnant women with epilepsy in a developing country.”
Kochen S, Salera C, Seni J. Open Neurol J (2011); 5:63-7. doi: 10.2174/1874205X01105010063.
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“A study of word finding difficulties in Spanish speakers with temporal lobe epilepsy.”
Lomlomdjian C, Solis P, Medel N, Kochen S. Epilepsy Res (2011); 97(1-2):37-44. doi: 0.1016/j.eplepsyres.2011.06.016.
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“Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry”
Tomson T, Battino D, Bonizzoni E, Craig J, Lindhout D, Sabers A, Perucca E, Vajda F, for the EURAP study group* (*Kochen Silvia).
The Lancet Neurology (2011); 10(7): 609-17. doi: 10.1016/S1474-4422(11)70107-7.
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“Embarazo y epilepsia en Argentina.”
Kochen S, Salera C, Seni j. Revista Neurolológica Argentina (2011); 03:156-61.
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“Impact of head models in N170 component source imaging: results in control subjects and ADHD patients”
Beltrachini L, Blenkmann A, von Ellenrieder N, Petroni A, Urquina H, Manes F, Ibáñez A, Muravchik CH, Kochen S. Journal of Physics: Conference Series (2011); 332: 012019.
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“Síntomas negativos en pacientes con trastornos psiquiátricos no esquizofrénicos”
Donnoli V, Moroni M, Cohen D, Chisari Rocha L, Marleta M, Sepich Dalmeida T, Bonani M, D'alessio L. Vertex Revista Argentina de Psiquiatría (2011); 22:262-67.
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“Actualización sobre la clasificación de las crisis Epilépticas”.
Yacoubian EM, Kochen S. Revista Chilena de Epilepsia (2011) Nº1 - Junio 2011

"Dieta Cetogénica en pacientes adultos con epilepsia refractaria”
Martin D, Kochen S. Revista Chilena de Epilepsia (2011)- Nº1 - Junio 2011

2010

“La situación de las mujeres en el arte de curar”
Kochen, S. Revista Neurológica Argentina (2010); 2(4):219-20.
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“ApoE epsilon4 genotype and the age at onset of temporal lobe epilepsy: a case-control study and meta-analysis”.
Kauffman MA, Consalvo D, Moron DG, Lereis VP, Kochen S. Epilepsy Res (2010); 90(3):234-9.
doi: 10.1016/j.eplepsyres.2010.05.007.
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“Doublecortin (DCX) immunoreactivity in hippocampus of chronic refractory temporal lobe epilepsy patients with hippocampal sclerosis.”
D'Alessio L, Konopka H, López EM, Seoane E, Consalvo D, Oddo S, Kochen S, López-Costa JJ. Seizure (2010);19(9):567-72. doi: 10.1016/j.seizure.2010.09.004.
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2009

“Psychotic disorders in Argentine patients with refractory temporal lobe epilepsy: A case–control study”
D’Alessio L, Giagante B, Papayannis C, Oddo S, Silva W, Solís P, Donnoli V, Kauffman MA, Consalvo D, Zieher LM, Kochen S. Epilepsy & Behavior (2009); 14(4):604–609. doi: 10.1016/j.yebeh.2009.02.019.
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“ApoE e 4 is not associated with posictal confusion in patients with mesial temporal lobe epilepsy with hippocampal sclerosis”
Kauffman M, Pereyra da Silva N, Consalvo D, Kochen S. Short communication, Epilepsy Research (2009); 85(2-3):311-3. doi: 10.1016/j.eplepsyres.2009.03.012.
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"Serotonin Transporter Gene Variation and Refractory Mesial Temporal Epilepsy with Hippocampal Sclerosis"
Kauffman M, Consalvo D, Gonzalez-Morón D, Aguirre F, D’Alessio L, Kochen S. Epilepsy Research (2009); 85(2-3):231-4. doi: 10.1016/j.eplepsyres.2009.03.010.
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“Utilization of Antiepileptic Drugs during Pregnancy: Comparative Patterns in 38 Countries Based on Data from the EURAP Registry”
“The EURAP Study Group.” (Kochen S es coordinadora por Argentina e integrante del Grupo) Epilepsia (2009); 50(10): 2305-9. doi: 10.1111/j.1528-1167.2009.02093.x.
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“Latin American Brain Mapping Network (LABMAN)”
Uludag K, Evans AC, Della-Maggiore V, Kochen S, Amaro E, Sierra O, Valdés-Hernandez P, Medina V, Valdés-Sosa P. NeuroImage (2009); 47(1):312-3. doi: 10.1016/j.neuroimage.2009.03.030.
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"Approximate Average Head Models for EEG Source Imaging"
Valdés-Hernández PA; von Ellenrieder N; Ojeda-Gonzalez A; Kochen S; Alemán-Gómez Y; Muravchik C; Valdés-Sosa PA. Journal of Neuroscience Methods (2009); 185(1):125-32. doi: 10.1016/j.jneumeth.2009.09.005.
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"Psychogenic non epileptic seizures after head injury: a case report"
Sce´vola L, D’Alessio L, Saferstein D, Centurio´n E, Consalvo D, Kochen S. Case Report Med (2009), Article ID 712813, 4 pages. doi: 10.1155/2009/712813.
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“El alelo e4 de la apolipoproteína modificaría el "período silente" del desarrollo de la epilepsia mesial temporal con esclerosis del hipocampo”
Kauffman MA, Consalvo D, Gonzalez-Moron D, Pujol V, Solís P, Oddo S, Lomlomdjian C, Kochen S. Revista Neurológica Argentina (2009); 1(2):148-154.
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“Heterotopía en banda o doble corteza, reporte de caso”
Melcon CM, Consalvo D, Centurión E, Papayanis C, Kauffman M, Kochen S. Revista Neurológica Argentina (2009); 1: 47-49.
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“Sistemas nacionales de investigación para la salud en América Latina: una revisión de 14 países.”
Alger J, Becerra-Posada F, Kennedy A, Martinelli E, Cuervo LG; Grupo Colaborativo de la Primera Conferencia Latinoamericana de Investigación e Innovación para la Salud (Kochen Silvia)
Rev Panam Salud Publica (2009); 26(5):447-57. Spanish.
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2008

“Clinical spectrum and difficulties in management of hypothalamic hamartoma in a developing country”
Papayannis CE, Consalvo D, Seifer G, Kauffman MA, Silva W, Kochen S. Acta Neurol Scand (2008); 10: 1111/1600.
doi: 10.1111/j.1600-0404.2008.01016.x.
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“Transcriptionally Less Active Prodynorphin Promoter Alleles are Associated with Temporal Lobe Epilepsy: A Case-Control Study and Meta-Analysis”
Kauffman MA, Consalvo D, Gonzalez Moron D, Kochen S. Disease Markers (2008); 24:135–140
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“GABABR1 (G1465A) Gene Variation and Temporal Lobe Epilepsy Controversy: New Evidence”
Kauffman M, Levy EM, Consalvo S, Mordoh J, Kochen S. Seizure (2008); 17:567-71.
doi: 10.1016/j.seizure.2007.12.006.
[Download]

“Analysis of psychotic disorders in patients with refractory partial epilepsy, psychiatric diagnoses and clinical aspects”
D’Alessio L, Giagante B, Ibarra V, Papayannis C, Oddo S, Solís P, Consalvo D, Silva W, Donnoli V, Zieher LM, Kochen S. Actas Esp Psiquiatr (2008); 36(3):138-143
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“Association study between interleukin 1_ gene and epileptic disorders: a HuGe review and meta-analysis”
Kauffman MA, Gonzalez Moron D, Consalvo D, Bello R, Kochen S. Genetics IN Medicine (2008); 10(2):83-88
doi: 10.1097/GIM.0b013e318161317c.
[Download]

“Genotipificación del gen del recaptador de la serotonina y respuesta al tratamiento en la epilepsia mesial temporal con esclerosis del hipocampo ¿Pronóstico Molecular?”
Kauffman MA, Consalvo D, Gonzalez Moron D, Aguirre F, D'Alessio L, Kochen S. Rev Neurol Arg (2008); 33(1):22-7.
[Download]

2007

“Prevalence and Clinical Features of Epilepsy in Argentine. A Community-Based Study”
Melcon MO, Kochen S, Vergara RH. Neuroepidemiology (2007); 28:8-15
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“NADPH diaphorase reactive neurons in temporal lobe cortex of patients with intractable epilepsy and hippocampal sclerosis”
D'Alessio L, Lopez-Costa JJ, Konopka H, Consalvo D, Seoane E, Lopez ME, Guelman ML, Kochen S, Zieher LM.
Epilepsy Research (2007); 74, 228-231
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“Recommendations regarding the requirements and applications for long-term recordings in epilepsy”
Velis D, Plouin P, Gotman J, Battaglia G, Litt B, Renault B, Lennertz K, Velis D, Kochen S, Plouin P, Nakasato N, Lopes da Silva F, ILAE DMC Subcommittee on Neurophysiology. Epilepsia (2007); 48 (2): 379–384.
[Download]

“Genética de la epilepsia del lóbulo temporal”
Kauffman MA, Consalvo S, Kochen S. Psicofarmacología (2007); 46:16-21. Editorial Sciens
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“Asociación entre alelos transcripcionalmente deficientes del gen de la prodinorfina y el desarrollo de epilepsia del lóbulo temporal”
Kauffman MA, Consalvo D, Gonzalez-Moron D, Kochen S. Revista Neurológica Argentina (2007); 32: 40-46
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2006

“El polimorfismo G1465A del gen GABBR1 es un marcador de riesgo para el desarrollo de epilepsia mesial temporal con esclerosis del hipocampo”
Kauffman MA, Consalvo D, Papayannis CE, Mordoh J, kochen S, Levy EM. Revista Neurológica (Arg), (2006); 31(1): 25-31. Revista del Hospital J. M. Ramos Mejía,. Edición Electrónica - Volumen X - Nº4 – 2005. Trabajos premiados en la Jornadas Interdisciplinarias.
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“Psychiatric disorders in patients with psychogenic non epileptic seizures, with and without comorbid epilepsy”
D’Alessio L, Giagante B, Oddo S, Silva W, Solis P, Consalvo D, Kochen S. Seizure (2006); 15(5):333-9
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“Automatic Detection of Interictal Spikes using Data Mining Models”
Valenti P, Cazamajou E, Scarpettini M, Aizemberg A, Silva W, Kochen S. Journal of Neurosciences Methods (2006); 150(1): 105-110.
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“Seizure control and treatment in pregnancy”
Observations from the EURAP Epilepsy Pregnancy Registry
The EURAP Study Group* (Kochen S.) (Lista Completa en www.neurology.org appendix E-1)
Neurology (2006); 66(3):354-360.
[Download]

“Periventricular nodular and subcortical neuronal heterotopia in adult epileptic patients”
Consalvo DE, Kochen SS, Alurralde A, Centurion E, Salgado PA, Saidon P, Sica RE.
Medicina (B Aires) (2006); 66 (2):101-7.
[Download]

“Investigación sanitaria: políticas, recursos y voluntades”
Ortiz Z, Olmos M, Ramos S, Kochen S, Segura E. Revista del ITAES (Instituto Técnico para la Acreditación de Servicios de Salud) (2006); Vol 8 Nº 1
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2005

“Normas de diagnóstico y tratamiento de epilepsia”.
Kochen S. Boletín del Programa Remediar del Ministerio de Salud de la Nación (2005)
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“Prognosis of Epilepsy in a Community-Based Study: Eight years of Follow-up in an Argentine Community”
Kochen S, Melcon MO. Acta Scandinavica Neurologica (2005); 112(6): 370 - 374.
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“Visual defects associated with vigabatrin: a study of epileptic argentine patients”
Moreno M, Giagante B, Saidon P, Kochen S, Benozzi J, Rosenstein R. Can J Neurol Sci. (2005); 32(4): 459-64.
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2004

“Prediction of epileptic seizures using accumulated energy in a multiresolution framework”
Gigola S, Ortiz F, D'Attellis CE, Silva W, Kochen S. Journal of Neuroscience Methods (2004); 138(1-2): 107-11.
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2001

"Clinical features and prognosis of nonepileptic seizures in a developing country"
Silva W, Giagante B, Saizar R, D'Alessio L, Oddo S, Consalvo D, Saidón P, Kochen S. Epilepsia (2001); 42(3): 398-401.
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"Psicosis Esquizofreniforme Tras Cirugía de Epilepsia. Un Caso del Fenómeno de Normalización Forzada."
D'Alessio L, Kochen S. Actas Esp Psiquiatr (2001); 29(4):00
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CAPITULOS DE LIBROS

"Cortical deficits in emotion processing for faces in adults with ADHD: Its relation to social cognition and executive functioning". Ibañez A; Petroni A; Urquina H; Torralva T; Blenkmann A; Beltrachini L; Muravchik C; Baez S; Cetkovich M; Torrente F; Hurtado E; Guex R; Sigman M; Lischinsky A; Manes F. Capítulo publicado en Social Neuroscience of Psychiatric Disorders. Londres: PSYCHOLOGY PRESS. 2012. ISBN 1848727577

"Carga alostática y estrés" en Carga Alostática: parte I. D`Alessio L. Laboratorios Gador editores, Buenos Aires, Polemos Editorial, 2011. Pág 9-21.

"Carga alostática y medicina traslacional; cerebro, circuitos cerebrales y estrés psicosocial" en Carga Alostática: parte II. D`Alessio L. Laboratorios Gador editores, Buenos Aires, Polemos Editorial, 2011. pág 7-29.

Libro: “Manifesto: Pela universalidade da divulgação da produção científica” Pais-Ribeiro JL, Martins-da-Silva A, Kochen S, da Mota Gomes M, Vela-Bueno A, Silvério Marques M. 1ª Edição, Novembro 2011. ISBN- 978-989-8463-29-6. Lisboa: Placebo, Editora LDA.

Libro: “Las crisis epilépticas” Yacubian EMT y Kochen S, Editorial Casa Leitura Médica. 2010
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"Tratamiento psicofarmacológico de los trastornos psicóticos en sus distintas etapas evolutivas: Fase aguda de descompensación".
D`Alessio L, Sanchez Toranzo A, Hansen F, Avigo L en Tratado de Psicofarmacología y Neurociencia, Volumen I, Esquizofrenia y otras psicosis. Neurobiología y terapéuticas. LM Zieher - MC Brió editores, Buenos Aires, Sciens Editorial 2009. ISBN 978-987-23649-3-9; pág 181-198.

"Tratamiento farmacológico de mantenimiento de los trastornos psicóticos: fase crónica compensada".
Sánchez Toranzo A, Hansen F, D`Alessio L en Tratrado de Psicofarmacología y Neurociencia, Volumen I, Esquizofrenia y otras psicosis. Neurobiología y terapéuticas. LM Zieher - MC Brió editores, Buenos Aires, Sciens Editorial 2009. ISBN 978-987-23649-3-9; 199- 214.

"Mecanismos Neurobiológicos de la Resiliencia". D`Alessio L. Buenos Aires, Editorial Polemos, primera edición 2009; pág 1-69.

"Conducción del impulso nervioso en fibras desmielinizadas. Conceptos neurofisiológicos". Capitulo 3, Seifer Gustavo, A.M. Villa en Esclerosis Multiple: Conceptos básicos y clínicos. AM Villa, J Correale, O Garcea. Ed. Dunken. 2008

"Aspectos neurobiológicos de los trastornos conductuales en la Epilepsia. Uso racional de psicofármacos en niños y adolescentes con epilepsia y trastornos de conducta". D´Alessio L, Brió M C, en Psicofármacos y Neurociencia en Pediatría. María Cristina Brió editores, Buenos Aires, Sciens Editorial 2007; 331-353. ISBN978-987-23649-0-8

"Ciencia, tecnología y género: Informe internacional”. Fernandez-Polcuch E, Kochen S, Helena-Maria M, Liqun Liu, Gudrun Maass, Martínez E. Ediciones UNESCO, 2007
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"Propuesta de construcción de indicadores en el sector de ciencia y tecnología con perspectiva de género". Kochen S, Franchi A, Maffía D y Atrio J. En Indicadores de Ciencia y Tecnología en Iberoamérica, Agenda 2005. Editores: Mario Albornoz y Diego Ratto.
RICyT (CYTED - OEA). 2005. ISBN: 987-20443-1-7
[Download]

"Fármacos Antiepilépticos". Saidón P, D´Alessio L, Mazaira S. en Colección de Farmacología Clínica: Neuropsicofarmacología Clínica. Zieher LM, Alvano S, Ianantuono R, Fadel D, Serra H, Editores. Gráfica Siltor. Tercera Edición, Buenos Aires 2004. pág 376-390. ISBN 9879643569.

“Wavelet analysis preceding seizures”. Kochen S., Giagante B., DAtellis C., Sirne R., Roitman J. Advances en Clinical Neurophysiology (Suppl.), 2002, Vol. 54; Chapter 67; 457-61. 2002 Elsevier Science B.V.

“La situación de las mujeres en el sector científicotecnológico en América Latina. Principales indicadores de género.”
Kochen S.; Franchi A.; Maffía D. Cuadernos de Iberoamérica: Las Mujeres en el sistema de Ciencia y Tecnología. Editora Eulalia Perez Sedeño. 2001, Organización de Estados Iberoamericanos (OEI)

“Las mujeres y la ciencia” Kochen S. en La Neurología y los Neurólogos Argentinos (el otro lado) Sociedad Neurológica Argentina, Editores J.C. Ortiz de Zárate; 1998

"Epilepsia", Kochen S. en Texto de Neurología Clínica, Editorial López. 1era edición 1994. pags 103-133

PUBLICACIONES EN SUPLEMENTOS DE REVISTAS NACIONALES E INTERNACIONALES,
CON REFERATO Y COMUNICACIONES A CONGRESOS 2012

"Utility of a Specific Instrument to Evaluate Antiepileptic Drugs Toxicity".
Pereira de Silva N. F., Caballero Murguia P., Morello M. T., Kochen S., Saidon P. www.aesnet.org. Abst. 2.225, 2012

"Valoración De Cambios Cognitivos Con Topiramato En Pacientes Con Epilepsia".
Pereira De Silva N, Medel N, Solis P, Kochen S, Saidon P. Neurología Argentina. Volumen 4. Suplemento. 2012

"Utilidad De La Escala De Somnoliencia De Epworth Como Herramienta Predictiva De SAHOS".
López Vicchi M, Persi G, Pereira De Silva N, Campuzano M, Gatto E. Neurología Argentina. Volumen 4. Supl. 2012

“Evaluation of source localization algorithms from eeg intracranial recordings simulated with physiologically plausible neuronal populations model”. Blenkmann Alejandro; Beltrachini Leandro; Princich Juan Pablo; Muravchik Carlos; Kochen Silvia. Ecuador. Quito. 2012. VII Congreso Latinoamericano de Epilepsia. Libro de Actas del Congreso.

“Disprosodia ictal e interictal con recuperación post Lobectomía Temporal Anterior Derecha. Descripción de un caso.”
Lomlomdjian, C., Múnera C., Valeriano L., Terpiluk V., Medel, N. Solis P. y Kochen, S. Póster. XLIX Congreso Argentino de Neurología.
Sheraton Hotel Mar del Plata. 5-7 Noviembre 2012.

"Evaluación del lenguaje en hemisferio derecho. Estudio de pacientes con Epilepsia del Lóbulo Temporal Derecho.”
Lomlomdjian, C., Múnera C., Valeriano L., Terpiluk V., Medel, N. Solis P. y Kochen, S. Póster. XLIX Congreso Argentino de Neurología.
Sheraton Hotel Mar del Plata. 5-7 Noviembre 2012.

"Afasia cruzada posterior a lobectomía temporal anterior derecha en un paciente con epilepsia del lóbulo temporal mesial".
Múnera C, Lomlomdjian C, Solís P, Medel N, Seoane E, Kochen S. Póster. VII Congreso Latinoamericano de Epilepsia. Quito Ecuador.
14-17 Noviembre 2012.

"Validación de un protocolo de evaluación de la memoria autobiográfica en pacientes de habla hispana con epilepsia"
Múnera C, Lomlomdjian C, Solís P, Medel N, Kochen S. Póster. XLIX Congreso Argentino de Neurología. Mar del Plata, Argentina. 7-10 Noviembre 2012.

" Validación de un protocolo de evaluación de la memoria autobiográfica en pacientes de habla hispana con epilepsia "
Múnera C, Lomlomdjian C, Solís P, Medel N, Kochen S. Póster. X Congreso Argentino de Neuropsicología SONEPSA. Buenos Aires, Argentina. 31 Oct - 3 Noviembre 2012.

2011

“Utilidad de un Instrumento Especifico para Evaluar Toxicidad Asociada a Daes. Morello M.T., Caballero Murguia P., Pereira de Silva N., Kochen S., Saidon P.
48 Congreso Argentino de Neurología. Sociedad Neurológica Argentina Revista Neurológica Argentina, Supl., 3; S1(2011).

"Impact of head models in N170 component source imaging: results in control subjects and ADHD patients".
Beltrachini L; Blenkmann A; Von Ellenrieder N; Petroni A; Urquina H; Manes F; Ibañez A; Muravchik C.
XVIII Congreso Argentino de Bioingeniería. Sociedad Argentina de Bioingeniería. Libro de Actas del Congreso, 72.
Mar del Plata, Argentina. 2011.

"Evaluación de sLORETA para la resolución del problema inverso en o o ECoG utilizando modelos de poblaciones neuronales fisiológicamente plausibles".
Blenkmann A; Beltrachini L; Von Ellenrieder N; Kochen S; Muravchik C. XIV Reunión de trabajo en Procesamiento de la información y Control (RPIC2011). Paraná, Argentina. Noviembre 2011

“Afasia cruzada post lobectomía temporal anterior derecha en un paciente con epilepsia del lóbulo temporal”
Munera C., Lomlomdjian C., Solis P., Medel N., Kochen S. Póster. XLVIII Congreso Argentino de Neurología. Sociedad Neurológica Argentina Revista Neurológica Argentina, Supl., 3; S1(2011). Córdoba, Argentina. 2-4 Noviembre 2011.

“Estudio de los aspectos lingüísticos y sociales de la comunicación en epilepsia del lóbulo temporal” Lomlomdjian C., Djanikian L., Solis P., Munera C., Medel N., Kochen S. Póster. XLVIII Congreso Argentino de Neurología. Revista Neurológica Argentina, Supl., 3; S1(2011). Córdoba, Argentina. 2-4 Noviembre 2011.

“Diagnóstico Molecular de Encefalomiopatías Mitocondriales: Evaluación de una Plataforma de Pirosecuenciación Masiva”. Kauffman M, Gonzalez Moron D, Consalvo D, Westergaard G, Vazquez M, Mancini E, Taratuto A, Rey RC, Kochen S (2011). 41 Reunión Anual Sociedad Argentina de Investigación Clínica. Medicina 71, S3

“Utilización de una plataforma genómica para el diagnóstico de patologías neurogenéticas: malformaciones del desarrollo cortical y trastornos mitocondriales”. Kauffman M, Gonzalez Moron D, Consalvo D, Westergaard G, Vazquez M, Mancini E, Taratuto A, Rey RC, Kochen S (2011). 48 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Neurología Argentina, 2; S1

“Uso de la FDG-TEP en epilepsia temporal no lesional”. Consalvo D, Blumenkrantz Y, Princich J, Kauffman M, Oddo S, Kochen S, Rey R (2011). 48 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Neurología Argentina, 2; S1

“Análisis de alteraciones microestructurales de la sustancia blanca mediante imagines por tensor de difusión de RM displasias corticales focales”. Princich J, Consalvo D, Kauffman M, Seifer G, Blenkmann A, Kochen S (2011). 48 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Neurología Argentina, 2; S1

“¿Es la anatomía patológica un factor pronóstico para la lobectomía temporal en pacientes con esclerosis del hipocampo?”. Avalos JC, Silva BA, Consalvo D, Kauffman M, Konopka H, Seoane E, Rey R, Kochen S (2011). 48 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Neurología Argentina, 3; S1

“Correlación entre queja cognitiva, calidad de vida y evaluacion cognitiva en pacientes con Epilepsia”.
Pereira de Silva N; Medel N; Solís P; Kochen S; Saidón P.
48 Congreso Argentino de Neurología., Sociedad Neurológica Argentina Revista Neurológica Argentina, Supl., 3; S1(2011).

"Postoperative neuropsychological evaluation in patients with temporal lobe epilepsy in Argentina"
Silvia Oddo, Patricia Solis, Silvia Kochen
Epilepsia, Supl., 2011, 29th International Epilepsy Congress

“Clinical and neurophysiological analysis of adults patients with epileptic seizures only during sleep”.
Pereira de Silva N, Rodríguez SA, Janota FR, Rosito N, Kochen S. 29th International Epilepsia, Supl., 2011, 29th International Epilepsy Congress, Roma, Italia

2010

"Método de localización semiautomática de electrodos intracraneales a partir de imágenes de TAC y RM".
Blenkmann A; Seifer G; Princich JP; Consalvo D; Kochen S; Muravchik C. XLVII Congreso Argentino de Neurología. Sociedad Neurológica Argentina. Mar del Plata, Argentina. Diciembre 2010.

"Detectar y Cuantificar Automáticamente las Alteraciones de la Sustancia Blanca Asociadas a las D.C.F.".
Princich JP; Wassermann D; Seifer G; Blenkmann A; Consalvo D; Kochen S. XLVII Congreso Argentino de Neurología. Sociedad Neurológica Argentina. Mar del Plata, Argentina. 2010.

"Reorganización de la sustancia blanca distal a las Displasias Corticales Focales (DCF) en pacientes con epilepsia refractaria detectada a través de Imágenes por Tensor de Difusión (ITD) en Resonancia Magnética (RM)".
Princich JP; Seifer G; Blenkmann A; Consalvo D; Kochen S. 6to Congreso Latinoamericano de Epilepsia. International League Against Epilepsy. Cartagena, Colombia. 2010.

“Ácido quenodesoxicólico, un eficaz fármaco anti-convulsivo: Epilepsia refractaria y Xantomatosis Cerebrotendinosa”.
Kauffman M, Gonzalez Moron D, Consalvo D, Szlago M, Schenone A, Kochen S (2010). 47 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Neurología Argentina, 2; S1

“Factores relacionados a la producción de reacciones adversas medicamentosas con el uso de drogas antiepilépticas en un sistema de buena práctica de farmacovigilancia en un hospital público de la ciudad de Bs. As”.
Pereira de Silva N, Kochen S, Saidon P. 47 Congreso Argentino de Neurología. Mar del Plata. 2010. Revista Neurológica Argentina, Supl. 1, 2; S1(2010).

“Estudio del ritmo circadiano en pacientes con crisis de epilepsia únicamente durante el sueño”.
Janota FR, Pereira de Silva N, Rodríguez SA, Avalos JC, Gonorazky H, Christie C, Rosito N, Vigo D, Cardinali D, Kochen S. (2010). 47 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Neurología Argentina, 2; S1

“Estigmas sobre epilepsia. una encuesta a poblacion general en el area de la Ciudad de Buenos Aires”.
Centurión E, Kochen S. (2010). 47 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Neurología Argentina, 2; S1

2009

"Algoritmo MUSIC para la localización de fuentes de actividad cerebral. Simulaciones y ejemplos".
Blenkmann A; Von Ellenrieder N; Seifer G; Princich JP; Kochen S; Muravchik C. XVII Congreso Argentino de Bioingeniería, SABI' 09. Sociedad Argentina de Bioingeniería. Rosario, Argentina. Octubre 2009.

"Determinación de la ubicación de electrodos de EEG basada en fotografías digitales".
Von Ellenrieder N; Beltrachini L; Blenkmann A; San Martin JP; Kochen S; Muravchik C.
Argentina. Buenos Aires. 2009. XIII Reunión de Trabajo en Procesamiento de la Información y Control. Reunión de Trabajo en Procesamiento de la Información y Control.

"Localización De Fuente Epileptogena En Un Paciente Con Esclerosis Hipocampal Y Patología Dual".
Seifer G; Blenkmann A; Consalvo D; Princich JP; Muravchik C; Kochen S. XLVI Congreso Argentino de Neurología. Sociedad Neurológica Argentina. Revista Neurológica Argentina, Vol. 1, Supl., Pag 45. Mar del Plata, Argentina. Octubre 2009.

“Resonancia Magnética Funcional en el estudio del lenguaje en epilepsia del lóbulo temporal ”.
Lomlomdjian C., Solis P., Oddo S., Benitez M., Consalvo D., Princich J.P, Eleta M., Kochen S. Congreso Argentino de Epilepsia, Centro de Convenciones Salguero Plaza. Póster. 20-21 de Agosto 2009.

“Comparación de la tarea de denominación por vía visual versus auditiva en pacientes con epilepsia del lóbulo temporal”
Lomlomdjian C., Solis P., Oddo S., Medel N.,Abusambra V., Abel C., Kochen S. XI Congreso de la Sociedad Latinoamericana de Neuropsicologia (SLAN). Póster. Puebla, Mexico 20-23 de Octubre de 2009.

“Resonancia Magnética Funcional: Aplicación en Epilepsia en un hospital público de Argentina.”
Lomlomdjian C., Oddo S., Solis P., Benitez M., Consalvo D., Princich J.P, Eleta M., Kochen S. XI Congreso de la Sociedad Latinoamericana de Neuropsicologia (SLAN). Póster. Puebla, México 20-23 de Octubre de 2009.

“Protocolo de evaluación neuropsicológica para candidatos a cirugía de la epilepsia”.
Solis P., Oddo S., Medel N., Lomlomdjian C., Consalvo D., Kochen S. XI Congreso de la Sociedad Latinoamericana de Neuropsicologia (SLAN). Póster. Puebla, México 20-23 de Octubre de 2009.

“Epilepsia del lóbulo temporal mesial y virus herpes 6 humano ¿hay alguna relación?”
Pujol Lereis V.A., Janota F., Jaureguiberry A., D’Allesio L., Kauffaman M.A., Acevedo M.A., Consalvo D., Saidón P., Seoane E., Mistchenko A., Rey R.C., Kochen S. Revista Neurológica Argentina, Vol. 1, Supl., Pág. 44., Octubre 2009

“Epilepsia del lóbulo temporal: valor lateralizador de las tareas de denominación visual vs. auditiva”.
Lomlomdjian C., Solís P., Oddo S., Medel N., Pereira N., Abusambra V., Abel C., Kochen S. Revista Neurológica Argentina, Vol. 1, Supl., Pág. 44-45., Octubre 2009

“Reorganización de la sustancia blanca distal a las displasias corticales focales (DFC) en pacientes con epilepsia refractaria detectada a través de imágenes por tensor de difusión (ITD) en resonancia magnética (RM)”
Princich J.P., Seifer G., Blenkmann A., Consalvo D., Kochen S. Revista Neurológica Argentina, Vol. 1, Supl., Pag 45. Octubre 2009

“Riesgo de malformación congénita en madre con epilepsia”
Seni J., Salera C., Escaray G., Kochen S. Revista Neurologica Argentina, Vol.1, Supl., Pag 46. Octubre 2009

“Alta recurrencia familiar de convulsiones febriles: descripción de 20 sujetos afecatodos en 2 familiares”
Kauffman M.A., Consalvo D., Oddo S., Seni J., Pereira-de Silva N., Kochen S. Vol.1, Supl., Pag 46. Octubre 2009

2008

"Localización de focos epileptógenos utilizando el método de dipolo equivalente de corriente (ECD) en pacientes con epilepsia y malformaciones del desarrollo cortical (MCD)".
Blenkmann A; Seifer G; Papayannis C; Consalvo D; Silva W; Muravchik C; Kochen S. 5to Congreso Latinoamericano de Epilepsia. International League Against Epilepsy. Montevideo, Uruguay. 2008.

"Determinación del área cortical necesaria para la visualización de la actividad interictal en el registro de scalp en un paciente con displasia cortical focal".
Seifer G; Blenkmann A; Consalvo D; Silva W; Muravchik C; Kochen S. XLV Congreso Argentino de Neurología. Sociedad Neurológica Argentina. Mar del Plata, Argentina. Revista Neurológica Argentina, Vol. 33, Supl. Diciembre 2008.

"Utilidad de las Imágenes por Tensor de Difusión (ITD) en las Displasias Corticales Focales".
Princich JP; Consalvo D; Seifer G; Blenkmann A; Oddo S; Solis P; Lomlomdjian C; Eleta M; Kochen S. 5to Congreso Latinoamericano de Epilepsia. International League Against Epilepsy. Montevideo, Uruguay. 2008.

"Reorganización de la sustancia blanca distal a las Displasias Corticales Focales (DCF) en pacientes con epilepsia refractaria detectada a través de Imágenes por Tensor de Difusión (ITD) en Resonancia Magnética (RM)".
Princich JP; Seifer G; Blenkmann A; Consalvo D; Kochen S. XLVI Congreso Argentino de Neurología. Sociedad Neurológica Argentina. Revista Argentina de Neurología. Argentina.
2008
“Epilepsy secondary to Hypothalamic Hamartomas: clinical manifestations and difficulties in its treatment in a developing country.”
Papayannis C; Consalvo D; Seifer G; Kauffman M; Silva W; Kochen S. 8th European Congress on Epileptology. Berlín, Alemania. 21 - 25 Septiembre 2008.

"Encefalitis de Rasmussen: descripción de las características anátomo-electro-clínicas en la forma de presentación en adultos".
Papayannis C, Consalvo D, Oddo S, Solis P, Galán M, Silvia W, Kochen S. 5º Congreso Latinoamericano de Epilepsia. Montevideo, Uruguay. 5-8 Noviembre 2008.

“Utilidad de las Imágenes por Tensor de Difusión (ITD) en las Displasias Corticales Focales”
Princich JP.; Consalvo D.; Seifer G.; Blenkman A.; Oddo S.; Solis P, Lomlomdjian C; Eleta M.; Kochen S. 5º Congreso Latinoamericano de Epilepsia. Montevideo, Uruguay. 5-8 Noviembre 2008.

“Determinación del área cortical necesaria para la visualización de la actividad interictal en el registro de scalp en un paciente con displasia cortical focal”.
Seifer G.; Blenkmann A.; Consalvo D.; Silva W.; Muravchik C.; Kochen. XLV Congreso Argentino de Neurología. Mar del Plata, Argentina. 2008.

“Localización de focos epileptógenos utilizando el método de dipolo equivalente de corriente (ECD) en pacientes con epilepsia y malformaciones del desarrollo cortical (MCD)”.
Blenkmann A.; Seifer G.; Papayannis C.; Consalvo D.; Silva W.; Muravchik C.; Kochen S. 5to Congreso Latinoamericano de Epilepsia. Uruguay. 2008.

"Pronóstico a largo plazo en la cirugía de la Epilepsia Temporal sintomática".
Papayannis C., Galan M.; Silva W.; Giagante B.; Consalvo C.; Oddo S.; Centurión E.; Solis P.; Saidón P.; Seoane E.; Kochen S. Congreso Nacional de Epilepsia, organizado por L.A.C.E., 21-22 Agosto 2008.

"Valor lateralizador de la semiología ictal y postictal en pacientes con epilepsia refractaria frontal".
Giagante B, Consalvo D, Kauffman M, Kochen S. 5º Congreso Latinoamericano de Epilepsia. Montevideo, Uruguay. Libro de Actas del Congreso. 2008.

"Prevalencia de los trastornos psicóticos en pacientes con epilepsia parcial refractaria candidatos a cirugía".
D`Alessio L, Giagante B, Kauffman M, Kochen S. 5º Congreso Latinoamericano de Epilepsia. Montevideo. Libro de Actas del Congreso. 2008.

"El alelo e4 de la apolipoproteína E modificaría el período silente del desarrollo de la epilepsia mesial temporal con esclerosis del hipocampo".
Kauffman M, Consalvo D, Gonzalez Moron D, Kochen S. 53 Reunión Anual de la Sociedad Argentina de Investigación Clínica. Medicina 88 (Suppl 2), 154 . 2008.

"Inmunoreactividad de la DCX (doblecortina) en el hipocampo de pacientes con epilepsia temporal y esclerosis hipocampal operados". D`Alessio L, Konopka, Kauffman M, Kochen S. 53º Reunión Anual de la Sociedad Argentina de Investigación Clínica. Medicina 88 (s2) 151. 2008.

"Doublecortin inmmunoreactiviy in human hippocampal sclerosis. American Academy of Epilepsy".
D`Alessio L, Kauffman M, Kochen S. Annual Meeting. Epilepsia 49 (s7) 463. 2008.

"Is neccesary to perform a video-eeg in the preoperative evaluation of mtle-hs patients?".
Consalvo D, Aguirre F, Kauffman M, Kochen S. American Academy of Epilepsy. Annual Meeting. Epilepsia 49 (s7) 36. 2008.

"Early Post-Marketing Pharmacovigilance of BLASTOFERON: An interferon beta 1a biosimilar".
Kauffman M, Papouchado M, Diez RA. 8th ISOP Annual Meeting. Drug Safety 31, 885. 2008.

"Revisión sistemática de los genes diferencialmente expresados en la epilepsia del lóbulo temporal". Kauffman M, Consalvo D, Kochen S. 5 Congreso Latinoamericano de Epilepsia, (2008). Montevideo. Epilepsia, suppl, 2008

"Serotonin Gene Transporter Variation and Prediction of Pharmacoresistance in Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis". Kauffman M, Consalvo D, Kochen S. 60 Annual Meeting of the American Academy of Neurology. Neurology, (2008) 70; S1:A221

"La Historia de la Epilepsia Hereditaria". Kauffman, MA; Consalvo, D; Kochen, S. Congreso Argentino de Neurología. Rev Neurol Arg 2008 33 Supl 1: 58. Sociedad Neurológica Argentina

“¿Es diferente la epilepsia en los pacientes adultos mayores?” Cámpora, N; Consalvo, D; Kauffman, M; Centurión, E; Saidón, P; Kochen, S. Revista Neurológica Argentina, Vol. 33, Supl., Diciembre 2008.

“Análisis de la respuesta al tratamiento farmacológico en la epilepsia secundaria a malformaciones del desarrollo cortical (MDC)”
Papayannis, C; Consalvo, D; Oddo, S; Centurión, E; Kauffman, M; Silva, W; Giagante, B; P, D’ Alessio, L; Saidon, P; Kochen, S. Revista Neurológica Argentina, Vol. 33, Supl., Diciembre 2008.

“El alelo Â4 de la apolipoproteína e modificaría el << > del desarrollo de la epilepsia mesial temporal con esclerosis del hipocampo” Kauffman, MA; Consalvo, D; González-Moron, D; Pujol, V; Solís, P; Oddo, S; Lomlomdjian, C; Kochen, S. Revista Neurológica Argentina, Vol. 33, Supl., Diciembre 2008.

“Manifestaciones clínicas ictales y postictales en epilepsia del lóbulo frontal: utilidad para determinar la lateralidad de la zona epileptógena” Giagante, B; Consalvo, D; Silva, W; Oddo, S; Solís, P; Ibarra, V; Tschopp, L; Salera, C; D´Alessio, l; Papayanis, C; Centurión, E; Saidón, P; Kauffman, M; Kochen, S. Revista Neurológica Argentina, Vol. 33, Supl., Diciembre 2008.

“Morbilidad asociadas al monitoreo video-eeg invasivo crónico en la cirugía de la epilepsia” Consalvo, D; Oddo, S; Salera, C; Centurión, E; Kochen, S Revista Neurológica Argentina, Vol. 33, Supl., Diciembre 2008.

2007

"Resonancia Magnética Funcional en Epilepsia del lobulo Temporal: Análisis del Lenguaje y la Memoria". Oddo S., Solis P., Consalvo D., Lomlomdjian C., Eleta M., Kochen S. Rev. Neurologica Arg. Supl. 2007. Pag. 62. XLIV Congreso Argentino de Neurología. Póster.

“Análisis de la memoria en pacientes con epilepsia temporal con y sin esclerosis hipocampal”
Lomlomdjian C, Solis P., Oddo S., Kochen S. Congreso Nacional de Epilepsia. Póster. 20-21 de Septiembre de 2007.

“La tarea de denominación en pacientes con epilepsia del lóbulo temporal. Modularidad y Plasticidad”
Solis P; Oddo S; Lomlomdjian C, Eleta M, Kochen, S. X Congreso de la Sociedad Latinoamericana de Neuropsicología. Póster. 6-9 de Noviembre de 2007.

"Depression in Refractory Temporal Lobe Epileptic Patients".
Papayannis C, D’Alessio L, Kauffman M, Kochen S (2007). American Epilepsy Society, Annual Meeting. Epilepsia, 48; S6:104.

"Prognostic Factors in Patients with Periventricular Nodular Heterotopia".
Consalvo D, Kauffman M, Kochen S (2007).American Epilepsy Society, Annual Meeting. Epilepsia, 48; S6:403

"Investigación clínica de los trastornos psicóticos en pacientes con epilepsia del lóbulo temporal refractaria candidatos a cirugía de la epilepsia".
D’Alessio L, Papayannis C, Kauffman M, Kochen S (2007). 52 Reunión Científica Anual de la Sociedad Argentina de Investigación Clínica, SAIC, Medicina, 67; S3:197

"Variación genética en la neurotransmisión serotoninérgica y el riesgo de epilepsia mesial temporal refractaria".
Kauffman M, Consalvo D, Kochen S (2007). 52 Reunión Científica Anual de la Sociedad Argentina de Investigación Clínica, SAIC, Medicina, 67; S3:141

"Determinación de la presencia de patrones electroclínicos en pacientes con esclerosis hipocampal plus".
Giagante B, Consalvo D, Papayannis C, Kauffman M, Kochen S (2007). 52 Reunión Científica Anual de la Sociedad Argentina de Investigación Clínica, SAIC, Medicina, 67; S3:102

"Genotipificación del gen del recaptador de la serotonina y respuesta al tratamiento en la epilepsia mesial temporal con esclerosis del hipocampo ¿Pronóstico molecular?".
Kauffman M, Consalvo D, Kochen S (2007). 44 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Revista Neurologica Argentina, 32; S1:61

"Espectro clínico de la epilepsia con convulsiones febriles plus".
Melcon C, Kauffman M, Kochen S (2007). 44 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Revista Neurologica Argentina, 32; S1:60

"Discontinuación de drogas anticomiciales en pacientes libre de crisis: pronóstico de recurrencia".
Papayannis C, Kauffman M, Kochen S (2007). 44 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Revista Neurologica Argentina, 32; S1:38

"Depresión e intentos de suicidio en pacientes con epilepsia del lóbulo temporal candidatos a cirugía de la epilepsia". D'Alessio L, Kauffman M, Kochen S (2007). 44 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Revista Neurologica Argentina, 32; S1:37

"Análisis de patrones electroclínicos en el inicio de crisis en pacientes con esclerosis hipocampal plus".
Giagante B, Kauffman M, Kochen S (2007). 44 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Revista Neurologica Argentina, 32; S1:36

¿Es necesario realizar un video-eeg en la evaluación prequirurgica de la epilepsia temporal mesial con esclerosis del hipocampo?.
Aguirre F, Kauffman M, Kochen S (2007). 44 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Revista Neurologica Argentina, 32; S1:36

"Creutzfeldt-Jakob disease E200K en argentina".
Begue C, Kauffman M, Taratuto A (2007). 44 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Revista Neurologica Argentina, 32; S1:1

"Investigación de la asociación entre el polimorfismo R271C del gen KCNJ10 y el desarrollo de epilepsia del lóbulo temporal con esclerosis del hipocampo".
Kauffman M, Consalvo D, Kochen S (2007). 2 Congreso de la liga argentina contra la epilepsia.

"Espectro clínico y dificultades en el manejo de pacientes con epilepsia secundaria a hamartomas hipotalámicos: presentación de una serie de casos".
Papayannis C, Kauffman M, Kochen S (2007). 2 Congreso de la liga argentina contra la epilepsia.

"Patrones electroclinicos en pacientes con esclerosis hipocampal plus".
Giagante B, Kauffman M, Kochen S (2007). 2 Congreso de la liga argentina contra la epilepsia.

"Transcriptionally Deficient Alleles of Prodynorphin Gene and the Risk To Develop Temporal Lobe Epilepsy".
Kauffman M, Consalvo D, Gonzalez Moron D, Kochen S (2007). 59th Annual Meeting, American Academy of Neurology, Neurology 68; S1

"Characterization of the Interferon Beta Regulated Gene Expression Profile in Lymphocytes from Multiple Sclerosis Patients".
Kauffman M, Yankilevich P, Barrero P, Diez RA, Sterin-Prync A (2007). 59th Annual Meeting, American Academy of Neurology, Neurology 68; S1

2006

"Interleukin 1b Gene Promoter Polymorphism Is Associated with Temporal Lobe Epilepsy: A Systematic Review and Meta Analysis".
Kauffman M, Gonzalez Moron D, Consalvo D (2006). 1st North American Regional Epilepsy Congress., American Epilepsy Society, Epilepsia, 47; S4:367

"Extrahippocampal Abnormalities in Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis".
Consalvo D, Kauffman M (2006). 1st North American Regional Epilepsy Congress, American Epilepsy Society, Epilepsia, 47; S4:246

"Construcción de una red poligénica y pleiotrópica implicada en la fisiopatología de la Esclerosis del Hipocampo".
Kauffman M, Aguirre F, Kochen S, Consalvo D (2006). 43 Congreso Argentino de Neurología., Sociedad Neurologica Argentina, Revista Neurologica Argentina, S1: 40

"Alelos Transcripcionalmente Dedicientes Del Gen De La Prodinorfina Modifican El Riesgo A Desarrollar Epilepsia Del Lóbulo Temporal".
Kauffman M, Consalvo D, Kochen S (2006). 51 Reunión Científica Anual de la Sociedad Argentina de Investigación Clínica, SAIC, Medicina, 66; S2:54

"Epilepsia Parcial Occipital Sintomática: Análisis de sus Características Clínicas y Electroencefalográficas en una serie de casos".
Papayannis C, Kauffman M (2006). 43 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Revista Neurologica Argentina, 31; S1:3

"Investigación de la Asociación entre el Polimorfismo -376A del Gen TNFA y el Riesgo a desarrollar Esclerosis Múltiple en Argentina"
Kauffman M, Villa AM (2006). 43 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Revista Neurológica Argentina, 31;S1:4

"Signos Meníngeos: De la herencia de nuestros antepasados a la sala de guardia"
Gonzalez Moron D, Kauffman M (2006). 43 Congreso Argentino de Neurología., Sociedad neurológica Argentina, Revista Neurológica Argentina, 31;S1:19

"El Polimorfismo -511T del gen de la interleukina 1bmodificaría el riesgo a padecer epilepsia del lóbulo temporal con esclerosis del hipocampo: una revisión sistemática y meta-análisis"
Kauffman M, Consalvo D, Kochen S (2006). 43 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, 31;S1:40

"Caracterización de la expresión génica inducidad por interferón beta en leucocitos de pacientes con esclerosis múltiple utilizando microarrays de genoma completo".
Kauffman M, Diez RA (2006). 43 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Revista Neurológica Argentina, 31;S1:46

"Análisis Comparativo de dos preparaciones farmacéuticas con interferón beta 1a en leucocitos de pacientes con esclerosis múltiple utilizando microarrays de genoma humano completo"
Steryn-Prync A, Kauffman M (2006). 43 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Revista Neurológica Argentina, 31;S1:45

"Familias con Epilepsia, Diferentes Síndromes Epilépticos"
Melcom C, Kauffman M, Kochen S (2006). 43 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Revista Neurológica Argentina, 31;S1:62

"Patrones clínicos registrados en pacientes con esclerosis hipocampal y pacientes con esclerosis hipocampal plus"
Giagante B, Kauffman M, Kochen S (2006). 43 Congreso Argentino de Neurología., Sociedad Neurológica Argentina, Revista Neurológica Argentina, 31;S1:63

"Utilidad del registro de video-eeg en el hospital ramos mejía"
Gil R, Kauffman M, Kochen S (2006). 43 Congreso Argentino de Neurología., Sociedad neurológica Argentina, Revista Neurológica Argentina, 31;S1:65

"Manifestaciones Neurológicas en pacientes con calcificaciones cerebrales".
Berdeja H, Kauffman M (2006). 43 Congreso Argentino de Neurología, Sociedad Neurológica Argentina, Revista Neurológica Argentina, 31;S1:68

"Is TNFA -376A SNP a population specific genetic risk marker of the susceptibility to develop multiple sclerosis?"
Kauffman M, Villa AM (2006). 22nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis., European Committee for Treatment and Research in Multiple Sclerosis, Multiple Sclerosis, 12; S1: S73

"A Genetic Variant in GABBR1 Gene is a Risk Factor to Develop Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis"
Kauffman M, Consalvo D, Kochen S (2006). 4 Congreso Latinoamericano de Epilepsia, Liga Internacional contra la Epilepsia, Libro de Abstracts del Congreso

"Epilepsia Secundaria a Malformaciones del Desarrollo Cortical (MDC): Analisis Comparativo de los Diferentes Subtipos de MDC."
Papayannis C, Kauffman M (2006). 4 Congreso Latinoamericano de Epilepsia, Internacional contra la Epilepsia, Libro de Abstracts del Congreso

"BLASTOFERON vs. REBIF: Whole genome pharmacodynamic similarity between two recombinant human interferon-beta 1a preparations"
Steryn-Prync A, Kauffman M (2006). 22nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis, European Committee for Treatment and Research in Multiple Sclerosis, Multiple Sclerosis, 12;S1:S208

"DSM IV PsychoticDisorders in Refractory Temporal Lobe Epileptic Patients"
D`Alessio L, Kauffman M, Kochen S (2006). 4 Congreso Latinoamericano de Epilepsia 2006., Liga Internacional contra la Epilepsia, Libro de Abstracts del Congreso

"Seguridad y cinética preclínicas de interferón beta-1a recombinante humano (blastoferon) en primates no humanos (cebus apella) y en ratones"
Diez RA, Kauffman M (2006). IV Congreso Latinoamericano para el tratamiento e investigación en Esclerosis Múltiple (LACTRIMS), Latin American Committee for Treatment and Research in Multiple Sclerosis, Revista de Neurología, 43; S1:8

"GABA (B) Receptor 1 Polymorphism (G1465A) Is a Marker of the Genetic Risk To Develop Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis"
Kauffman M, Consalvo D, Kochen S (2006). 58 Annual Meeting, American Academy of Neurology, Neurology, 66; S2:A 139

2005

"Implementación de algoritmos básicos para el análisis de la proliferación celular diferencial".
Benítez M; Blenkmann A; Cano R; Rapacioli M; Flores V.
Argentina. Paraná. 2005. XV Congreso Argentino de Bioingeniería (SABI 2005). Sociedad Argentina de Bioingeniería

"Un Análisis Biológico Evolutivo del Riesgo Genético a Desarrollar Esclerosis Múltiple"
Kauffman M, Villa AM (2005). 42 Congreso Argentino de Neurología, Sociedad Neurologica Argentina, Revista Neurologica Argentina, 30; S2:3, Published

"Análisis de las funciones cognitivas antes y después de la cirugía en pacientes con Epilepsia Temporal"
Oddo S, Kauffman M (2005). 50 Reunión Científica Anual de la Sociedad Argentina de Investigación Clínica, SAIC, Medicina, 65; S2: 71
"Paciente Epilépticos con Heterotopias Nodulares Periventriculares: Factores Pronosticos de Farmacorresistencia"
Consalvo D, Kauffman M (2005). 50 Reunión Científica Anual de la Sociedad Argentina de Investigación Clínica, SAIC, Medicina, 65; S2:155

"Estudio Comparativo de los Subtipos de Malformaciones del Desarrollo Cortical (MDC)"
Papayannis C, Kauffman M (2005). 50 Reunión Científica Anual de la Sociedad Argentina de Investigación Clínica, SAIC, Medicina, 65; S2: 159

"de Rinne y Weber. ¿Tienen Alguna Utilidad en la Práctica Clínica?"
Gonzalez Moron D, Kauffman M (2005). 42 Congreso Argentino de Neurología, Sociedad Neurologica Argentina, Revista Neurologica Argentina, 30; S2:7

"Epilepsia Temporal Unilateral sintomática Refractaria con Inicio Ictal Electroencefalográfico Contralateral"
Seifer G, Kauffman M (2005). 42 Congreso Argentino de Neurología, Sociedad Neurologica Argentina, Revista Neurologica Argentina, 30; S2: 8

"El Polimorfismo G1465A del Gen GABBR1 es un Marcador de Riesgo para el desarrollo de Epilepsia Mesial Temporal con Esclerosis del Hipocampo"
Kauffman M, Consalvo D, Kochen S (2005). 50 Reunión Científica Anual de la Sociedad Argentina de Investigación Clínica, SAIC, Medicina, 65; S1

"Un Caso de Agregación Familiar Serológica y Clínica de HTLV-1"
Seifer G, Kauffman M (2005). 42 Congreso Argentino de Neurología, Sociedad Neurologica Argentina, Revista Neurologica Argentina, 30; S2:35

Miastenia Gravis y Atrofia Muscular Aíslada Paraespinal"
Seifer G, Kauffman M (2005). 42 Congreso Argentino de Neurología, Sociedad Neurologica Argentina, Revista Neurologica Argentina, 30; S2:39

"Tumor Neuroectodérmico Primitivo/ Sarcoma de Ewing Intradural"
Jaureguiberry A, Kauffman M (2005). 42 Congreso Argentino de Neurología, Sociedad Neurologica Argentina, Revista Neurologica Argentina, 30; S2:53

Obtenidas desde 2005

- Premio Prof. Dr. Mauricio Goldenberg. 3° Jornadas de psiquiatría del Hospital Italiano de Buenos Aires. 23 y 24 de septiembre, 2005.“Crisis no epilépticas de origen psicógeno, diagnóstico psiquiátrico” D´Alessio L, Monteiro Gomes F, Scévola L, Giagante B, Oddo S, Solís P, Consalvo D, Silva W, Kochen S.

- Primer Premio Categoria Investigaciones Experimentales, Jornadas Interdisciplinarias Hospital Ramos Mejía. Septiembre 2005 “El polimorfismo G1465A del gen GABBR1 es un marcador de riesgo para el desarrollo de epilepsia mesial temporal con esclerosis del hipocampo”.
Marcelo A Kauffman, Damian Consalvo, Cristina E Papayannis, Jose Mordoh, Silvia S. Kochen y Biol. Estrella M Levy.

- Distinción por el Compromiso con la Salud desde el Hospital Público, en el Día Internacional de la Mujer otorgado por la Legislatura de Ciudad de Buenos Aires y de la Comsión de Mujer, Infancia, Adolescencia. Marzo 2006

- Premio “Ramos Mejía”, otorgado por la Sociedad Neurológica Argentina, 2006
“Asociación entre Alelos Transcripcionalmente Deficientes del gen de la Prodinorfina y el Desarrollo de Epilepsia del Lóbulo Temporal”. Kauffman M, Consalvo D, Gonzalez Moron D, Kochen S.

- 2007 Premio Sociedad Neurológica Argentina, Presentación del trabajo “Genotipificación del Gen del Recaptador de la Serotonina y Respuesta al Tratamiento en la Epilepsia Mesial Temporal con Esclerosis del Hipocampo ¿Pronóstico Molecular?”

- 2008, Premio Póster Edmundo Fisher, otorgado por la Asociación Argentina de Psiquiatría en el marco del 15 Congreso Internacional de Psiquiatría por el trabajo “Depresión e intentos de suicidio en pacientes con epilepsia del lóbulo temporal, candidatos a cirugía de la epilepsia”.

Damián Consalvo: “Determination of new epileptic syndroms through brain magnetic resonance” November 2005.

Silvia Oddo: "Characteristics of cognitive functions in the different epileptic syndroms". March 2006.

Brenda Giagante: “Determination of electro-clinic patterns in partial epilepsy” . April 2008

Luciana D’Allesio: “Psychosis and epilepsy: Clinical research of psychotic disorders in patients with temporal lobe epilepsy” March 2008

Marcelo Kauffman: "Research of genetic variability in mesial temporal lobe epilepsy with hippocampal sclerosis " year 2008.

Alejandro Blenkmann: “Source localization of brain activity”. March 2012.

Cristina Papayannis: “Study of epileptogenesis in epilepsy associated to malformations of cortical development” year 2012.